Neuropilin-1/BDCA-4/CD304

November 18th, 2008

Neuropilin-1 (Nrp-1) was recently identified as a possible surface marker for naturally occurring CD4+CD25+ regulatory T cells and is constitutively expressed on the cell irrespective of its activation status. Nrp-1 is a type 1 membrane protein with three unique functions. In neuronal cells, Nrp-1 binds the class 3 semaphorins, which are neuronal chemorepellents, and [...]

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